4R-Principle | Max-Planck-Gesellschaft https://www.mpg.de/10973438/4rs
The scientists at the Max Planck Society are committed to keeping the number of animal experiments as well as the strain on the animals as low as possible in the individual experiments. They apply the so-called 3R principle when planning and carrying out the experiments. ‚3R‘ stands for „Reduce, Refine, Replace“: the number of animals per experiment is reduced to the absolute minimum (‚Reduction‘); the performance of the experiments and the keeping of the animals optimized in such a way that the burden on the animals is as small as possible (‚Refinement‘); and animal experiments are replaced by alternative methods, whenever this is possible (‚Replacement‘).
age differently depending on where they are in the organ