Simply knotted https://www.mpg.de/4399871/silica_microspheres?page=1
Knots can now be tied systematically in the microscopic world. A team of scientists led by Uroš Tkalec from the Jožef Stefan Institute in Ljubljana (Slovenia), who has been working at the Max Planck Institute for Dynamics and Self-Organization in Göttingen (Germany) since September 2010, has now found a way to create every imaginable knot inside a liquid crystal. Starting points of the new method are tiny silica microspheres confined in thin liquid crystal layers.
within an only slightly thicker nematic liquid crystal film