Three patients with chronic paraplegia were able to
neurotechnology for treating paralysis Three patients with
With the grant, the genetics platform becomes part
With the grant, the genetics platform becomes part
Administering gene-editing treatment directly into the body could be a safe and effective way to treat a rare, life-threatening condition. Preliminary results from a landmark clinical trial suggest that CRISPR–Cas9 gene editing can be deployed directly into the body to treat disease.
In the trial, six people with a rare and fatal condition
A new study in mice documents frequent undesirable repeats of DNA insertions that are not detected using standard PCR analysis.
and researchers have been working to minimize them with
Januar 2018 Boosting cancer therapy with cross-dressed
November 2018 EPFL partners with Stanford to advance
In search of new ways to sequence human genomes and read critical alterations in DNA, researchers at Johns Hopkins Medicine say they have successfully used the gene cutting tool CRISPR to make cuts in DNA around lengthy tumor genes, which can be used to collect sequence information.
The researchers say that pairing CRISPR with tools
Until now all genome-wide sequencing technologies killed the cell to gain glimpses into its secrets. This technical limitation eliminated the possibility of follow-up analyses on a cell’s biological characteristics or molecular signatures once the cell was sequenced. A team led by Bart Deplancke, PhD, at EPFL, and Julia Vorholt, PhD, at ETH Zurich, has enhanced single-cell RNA sequencing technology such that the method can now obtain the sequences of thousands of transcripts from a single cell and thereby infer genetic activity without breaking the cell open.
microscopy approach—essentially an atomic force microscope with
Feng Zhang’s latest work delivers mRNA, gene therapy with
